The PySide project provides LGPL-licensed Python bindings for the Qt cross-platform application and UI framework. PySide Qt bindings allow both free open source and proprietary software development and ultimately aim to support all of the platforms as Qt itself.

Shiboken Threading Support Done

Shiboken now has proper threading support putting QtCore in an “almost done” state.
Read the mailing list announcement for more details.

Signals and Slots with Shiboken

The support for Qt’s signal/slot system in the Shiboken  fork of PySide has been completed! Happiness abound!
Read the mailing list announcement for more details.

PySide v0.2.3 – ‘Candy Mountain’ release

New Features:
– Support for Qt 4.6 release;
– Support for QtMultimedia;
– Support for Animation Framework;
– Support for State Machine Framework;
– New test-cases including QtMaemo5.
We hope you enjoy this new release! Feel free to contribute with comments,
bug reports and suggestions.

If you are interested in more than just using the PySide bindings then your wanting probably falls in one of these categories:
Create your own bindings for Qt4 based libraries
If you have a library built on top of Qt4 and want to make it available on Python, then check out the Binding Generator section on how [...]